Related Experiment Video
Updated: Oct 3, 2026

Experimental Infection of Mice with the Parasitic Nematode Strongyloides ratti
Published on: January 17, 2025
Invasive enteritis by Strongyloides stercoralis presenting as acute abdominal distress under corticosteroid therapy
M A Rodrigues1, R C Fróes, A Anefalos
1Division of Gastroenterology, Botucatu Medical School, University of the State of São Paulo, Brazil.
Abstract:
Overwhelming helminthiasis is still a problem in endemic areas, especially in immunocompromised patients. We report a case of invasive intestinal strongyloidiasis that was clinically expressed as acute abdominal distress in a 73-year-old man from São Paulo who had been receiving methylprednisone, 20 mg/day, for one year for osteoarthritis. A surgical specimen from the ileum revealed invasive enteritis with severe infestation by Strongyloides stercoralis. The patient died of sepsis 6 days after surgery. The possibility of invasive strongyloidiasis should be considered in the differential diagnosis of acute abdominal distress in patients undergoing immunosuppressive therapy.
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