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The hippocampus and declarative memory: cognitive mechanisms and neural codes.

H Eichenbaum1

  • 1Department of Psychology, Boston University, Boston, MA 02215, USA. hbe@bu.edu

Behavioural Brain Research
|November 24, 2001
PubMed
Summary

The hippocampus is crucial for linking distinct personal experiences into a flexible memory system. This brain region encodes events and places, forming a "memory space" for declarative memory.

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Area of Science:

  • Neuroscience
  • Cognitive Psychology

Background:

  • The hippocampus is known to mediate declarative memory in humans.
  • Fundamental cognitive mechanisms and neural representations of hippocampal-dependent memory remain unclear.

Purpose of the Study:

  • To propose a role for the hippocampus in encoding distinct experiences relationally.
  • To explain how the hippocampus supports flexible and inferential memory expression.

Main Methods:

  • Review of existing literature on declarative memory.
  • Analysis of emerging evidence from hippocampal neural activity recordings.

Main Results:

  • The hippocampus is proposed to link distinct personal experiences into an organized structure.
  • Hippocampal networks encode episodic memories as event sequences and associated places.

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  • Common events and places across episodes are also encoded by hippocampal networks.

    • Conclusions:

    • The hippocampus constructs a "memory space" by linking episodic representations.
    • This network of linked representations underlies key properties of declarative memory.