Detection of an mRNA polymorphism by differential display
1Department of Psychiatry, Vanderbilt University Medical Center, Nashville, TN, USA.
Molecular Biotechnology
|December 1, 2001
Abstract:
Differential Display (DD) technology was utilized to compare programs of gene expression in primary cultures of human skin fibroblasts from normal volunteers and patients diagnosed with melancholic depression. Polymorphic transcripts of a single gene differing by one tandem repeat sequence of four nucleotides (TGAT) in the 3' noncoding region were detected.
