Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Progestin-releasing intrauterine systems.

T Luukkainen1, P Pakarinen, J Toivonen

  • 1Steroid Research Laboratory, Institute of Biomedicine, University of Helsinki, Helsinki, Finland.

Seminars in Reproductive Medicine
|December 1, 2001
PubMed
Summary

The levonorgestrel-releasing intrauterine system (LNG IUS) effectively reduces menstrual bleeding by acting locally on the endometrium. While generally safe, it does not protect against sexually transmitted infections, necessitating condom use for at-risk individuals.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Systematic molecular and clinical analysis of uterine leiomyomas from fertile-aged women undergoing myomectomy.

Human reproduction (Oxford, England)·2020
Same author

Adaptive correlations between seed size and germination time.

Journal of mathematical biology·2018
Same author

In situ laser measurement of oxygen concentration and flue gas temperature utilizing chemical reaction kinetics.

Optics letters·2017
Same author

Thyrocyte-specific Dicer1 deficiency alters thyroid follicular organization and prevents goiter development.

Endocrinology·2015
Same author

Pituitary gonadotrophic hormone synthesis, secretion, subunit gene expression and cell structure in normal and follicle-stimulating hormone β knockout, follicle-stimulating hormone receptor knockout, luteinising hormone receptor knockout, hypogonadal and ovariectomised female mice.

Journal of neuroendocrinology·2014
Same author

Feasibility study of gel filtration as a separation method for blood serum proteins in combination with PIXE analysis.

Biological trace element research·2013

Area of Science:

  • Reproductive Health
  • Gynecology
  • Endocrinology

Background:

  • The levonorgestrel-releasing intrauterine system (LNG IUS) is a widely used contraceptive method.
  • Its mechanism involves local action on the endometrium, influencing menstrual patterns.

Purpose of the Study:

  • To detail the effects of the LNG IUS on the endometrium and menstrual blood loss.
  • To outline the associated health benefits and potential side effects of LNG IUS use.

Main Methods:

  • The study describes the physiological changes induced by local levonorgestrel release.
  • It analyzes the impact on endometrial proliferation and responsiveness to estrogen.
  • Observational data on menstrual blood loss, duration, and side effects are presented.

Related Experiment Videos

Main Results:

  • The LNG IUS causes endometrial transformation, leading to reduced menstrual blood loss and duration.
  • Amenorrhea is common after 9 months of use, despite normal ovarian function.
  • Reduced risk of pelvic inflammatory disease and potential side effects like mood changes, acne, and weight gain are noted.

Conclusions:

  • The LNG IUS is an effective contraceptive with significant benefits, including reduced menstrual bleeding and lower PID risk.
  • Endometrial suppression is the primary mechanism for these benefits.
  • Users must be informed about potential side effects and the lack of STI protection, recommending concurrent condom use when necessary.