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Deficits of spatial working memory in chronic schizophrenia
1Department of Neuropsychiatry, Kinki University School of Medicine, 377-2 Ohonohigashi, Osaka-Sayama 588-8511, Japan. okada@med.kindai.ac.jp
Schizophrenia Research
|December 1, 2001
Summary
Spatial working memory deficits in schizophrenia are not immutable. Cognitive interventions can improve performance in patients with schizophrenia, suggesting these deficits are not an inherent trait.
Area of Science:
- Neuroscience
- Cognitive Psychology
Background:
- Schizophrenia is often associated with cognitive deficits.
- Spatial working memory is crucial for daily functioning.
Purpose of the Study:
- To investigate if spatial working memory deficits are an inherent trait in schizophrenia.
- To determine if clinical status influences these deficits.
Main Methods:
- Two tasks assessing spatial working memory were administered to chronic schizophrenic patients, patients in remission, and normal controls.
- Task A involved tracking and reproducing a square outline.
- Task B involved tracking and reproducing sequential corners of a square.
Main Results:
- Chronic schizophrenic patients showed significant spatial working memory distortions compared to controls.
- Distortions were more pronounced in Task A than Task B for chronic patients.
- Schizophrenic patients in remission performed comparably to normal controls on both tasks.
Conclusions:
- Chronic schizophrenia is associated with significant spatial working memory deficits.
- These deficits are not immutable and can be improved with cognitive interventions.
- Spatial working memory deficits may not be an inherent trait in all schizophrenia patients.