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Updated: Oct 3, 2026

Chemotherapy-induced Vascular Toxicity - Real-time In vivo Imaging of Vessel Impairment
Published on: January 7, 2015
Blood flow after intraarterial infusion chemotherapy in a patient with advanced cervical cancer
Y Minagawa1, Y Onohara, H Takahashi
1Department of Obstetrics and Gynecology, Tottori Prefectural Central Hospital, Tottori, Japan. onohara@ruby.ocn.ne.jp
Abstract:
We presented a case of locally advanced cervical cancer treated by intraarterial infusion chemotherapy, and evaluated the blood flow of uterine arteries before and after chemotherapy by using a transvaginal ultrasonic color Doppler device. Pulsatility index (PI) of each uterine artery increased after first course of chemotherapy compared to that of before chemotherapy. But PI did not change after second course in spite of a significant reduction in tumor size. Blood flow change assessed by Doppler ultrasound may be a limited but useful parameter for the efficacy of neoadjuvant chemotherapy in patients with cervical cancer.

