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Polyvalent contact allergy to corticosteroids: a report of two cases
1Department of Dermatology, St Anne's, Hospital, Masaryk University, Brno, Czech Republic. sekr.dvk@fnusa.cz
Abstract:
Two cases of positive allergic reactions to eight patch-tested corticosteroid substances are reported. The patients were middle-aged women with a long history of contact dermatitis who had used topical corticosteroids for years. Pure corticosteroid substances were tested in therapeutic and 1% concentrations in ethanol and petrolatum. The intensity of reactions was different depending on the vehicle and concentration. Patients with hypersensitivity to several corticosteroid substances represent an important therapeutic problem.