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Hypotensive effect of chemical constituents from Aloe barbadensis
R Saleem1, S Faizi, B S Siddiqui
1Dr. H.M.I. Institute of Pharmacology and Herbal Sciences, Hamdard University, Karachi, Pakistan. rs127pk@yahoo.com
Planta Medica
|December 4, 2001
Abstract:
Hypotensive effects of aloeemodin, aloin A, elgonica dimer A and bisbenzopyran from Aloe barbadensis have been studied. Aloeemodin has emerged as a potent hypotensive agent in current pharmacological investigations and caused 26 %, 52 %, and 79 % falls in mean arterial blood pressure at the corresponding doses of 0.5, 1, and 3 mg/kg in rats. The paper also describes the absolute configuration of elgonica dimer A (1).