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Updated: Jul 16, 2026
10:23
Analysis of Epididymal Protein Synthesis and Secretion
Published on: August 25, 2018
Multiple functions of mouse zona pellucida glycoprotein mZP3, the sperm receptor
1Department of Biochemistry and Molecular Biology, Mount Sinai School of Medicine, New York, NY 10029-6574, USA. paul.wassarman@mssm.edu
Abstract:
Zona pellucida glycoprotein mZP3 is a structural glycoprotein, a sperm receptor, and an acrosome reaction-inducer. The latter two functions are mediated, at least in part, by mZP3 oligosaccharides. mZP3 is unique to mammalian eggs, from mice to humans, although related glycoproteins are found in vitelline envelopes of a variety of eggs, from fish to birds.
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