Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

External modulation of visual perception in humans.

A Antal1, M A Nitsche, W Paulus

  • 1Department of Clinical Neurophysiology, Georg-August University of Göttingen, Robert Koch Str. 40, 37070 Göttingen, Germany.

Neuroreport
|December 6, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Neurotherapy for children and adolescents with psychiatric disorders: a state-of-the-art umbrella review of selected clinical methodologies.

Neuroscience and biobehavioral reviews·2025
Same author

Enhancing the quality and reproducibility of research: Preferred Evaluation of Cognitive and Neuropsychological Studies - The PECANS statement for human studies.

Behavior research methods·2025
Same author

"The proof is in the pudding" Response to the Commentary: Do all studies using medical devices fall under the European Medical Device Regulation? Written by Dr. Roman Rethwilm, Prof. Dr. Martin Schecklmann, Dr. Desmond Agboada, Prof. Dr. Til Ole Bergmann, Prof. Dr. Wolfgang Seiberl.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2024
Same author

Policy, priorities and practice: 'Being in the room where it happens.' The European Brain Research Area and the Europe, Middle-East and Africa Chapter, International Federation of Clinical Neurophysiology.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2022
Same author

Evaluating Current Density Modeling of Non-Invasive Eye and Brain Electrical Stimulation Using Phosphene Thresholds.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society·2021
Same author

Isometric agonist and antagonist muscle activation interacts differently with 140-Hz transcranial alternating current stimulation aftereffects at different intensities.

Journal of neurophysiology·2021
Same journal

Electroacupuncture alleviates neuroinflammation and promotes recovery of neurological functions after intracerebral hemorrhage by modulating α7nAChR/JAK2/STAT3 signaling pathway.

Neuroreport·2026
Same journal

Non-cell-autonomous regulation of Bhlhb5 expression in cortical projection neurons by GABAergic interneuron development and position.

Neuroreport·2026
Same journal

C-C motif chemokine ligand 3 mediates inflammatory response via NLRP3 inflammasome and neuron damage after traumatic brain injury.

Neuroreport·2026
Same journal

Methyltransferase-like 14 alleviates neuronal ferroptosis in Alzheimer's disease by regulating the peroxiredoxin 6/apoptosis signal-regulating kinase 1 signaling pathway.

Neuroreport·2026
Same journal

Hand mental rotation reaction time reflects motor imagery strategy and predicts changes in finger dexterity after motor imagery.

Neuroreport·2026
Same journal

Functional exploration of metabotropic glycine receptors in cultured rat hippocampal slices.

Neuroreport·2026
See all related articles

Cathodal transcranial direct current stimulation (tDCS) temporarily reduced contrast sensitivity in healthy subjects. Anodal tDCS showed no effect, with vision returning to baseline post-stimulation, indicating transient visual modulation.

Area of Science:

  • Neuroscience
  • Ophthalmology
  • Neurostimulation

Background:

  • Transcranial direct current stimulation (tDCS) is a non-invasive brain stimulation technique.
  • Previous studies suggest tDCS can modulate neural excitability in the motor cortex.
  • The effects of tDCS on visual functions, specifically contrast sensitivity, are not well-established.

Purpose of the Study:

  • To investigate the effects of anodal and cathodal tDCS on static and dynamic contrast sensitivities (sCS and dCS).
  • To determine the duration of these effects and their reversibility.

Main Methods:

  • 15 healthy subjects underwent tDCS applied to the occipital cortex.
  • sCS and dCS were measured before, during, immediately after, and 10 minutes after stimulation.

Related Experiment Videos

  • Stimulation parameters included 7 minutes of anodal or cathodal tDCS at specific spatial and temporal frequencies (4 c/d and 4 Hz).

    • Main Results:

    • Cathodal tDCS significantly reduced both sCS and dCS during and immediately after stimulation.
    • Anodal tDCS did not produce significant changes in contrast sensitivity.
    • Contrast sensitivity returned to baseline levels within 10 minutes after cathodal tDCS cessation.

    Conclusions:

    • Weak direct current stimulation, particularly cathodal tDCS, can transiently alter primary visual functions like contrast detection.
    • These alterations are likely due to modulation of neural excitability in the visual cortex.
    • tDCS presents a promising non-invasive tool for inducing reversible, focal changes in the nervous system.