Related Experiment Video

Updated: Jul 19, 2026

A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
09:57

A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit

Published on: July 13, 2019

Short-term complications of central line placement in children with the human immunodeficiency virus

E R Island1, J A Church, D B Shaul

  • 1Departments of Surgery and Pediatrics, Childrens Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

Journal of Pediatric Surgery
|December 6, 2001
PubMed

Insights

Central venous catheter placement in children with human immunodeficiency virus (HIV) has a low complication rate (<15%). Careful preparation ensures the procedure

Area of Science:

  • Pediatric Surgery
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • Central venous catheters (CVCs) are crucial for managing pediatric patients, especially those with complex conditions like human immunodeficiency virus (HIV).
  • Understanding the risks associated with CVC placement in immunocompromised children is essential for optimizing patient care and outcomes.

Purpose of the Study:

  • To characterize the perioperative complications of central venous catheter (CVC) placement in children with human immunodeficiency virus (HIV).
  • To identify host and environmental factors associated with CVC-related complications in this vulnerable population.

Main Methods:

  • A retrospective chart review of HIV-infected children who underwent CVC placement between 1988 and 1998.
  • Analysis of complications occurring within one month of catheterization, including hemorrhage, infection, thrombosis, and malposition.

Main Results:

  • Eight out of 60 CVC placements (13%) in 40 HIV-positive children resulted in perioperative complications.
  • Complications included hemorrhage, site infection, catheter sepsis, thrombotic occlusion, and pleural effusion.
  • Severely immunosuppressed patients did not show a higher risk of infectious complications, suggesting CVC placement is feasible even in advanced HIV disease.

Conclusions:

  • The complication rate for CVC placement in HIV-infected children is low (<15%) but higher than in the general pediatric population.
  • Careful preoperative assessment and preparation allow for safe CVC placement, even in children with advanced HIV.
  • The study suggests that compromised immune status should not be a contraindication for CVC placement in pediatric HIV patients.
Abstract

More Related Videos

Hickman Catheter Use for Long-Term Vascular Access in a Preclinical Swine Model08:51

Hickman Catheter Use for Long-Term Vascular Access in a Preclinical Swine Model

Published on: March 31, 2023

Computed Tomography (CT) Guided Implantation of a Totally Implantable Venous Access Port (TIVAP) through Subclavian Vein05:51

Computed Tomography (CT) Guided Implantation of a Totally Implantable Venous Access Port (TIVAP) through Subclavian Vein

Published on: January 13, 2026

Related Concept Videos

Immunodeficiency Diseases01:25

Immunodeficiency Diseases

Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency disorders...
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Parentral Nutrition: Centeral and Peripheral Parental Nutrition01:27

Parentral Nutrition: Centeral and Peripheral Parental Nutrition

Parenteral Nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the digestive system. It is commonly used for individuals with severe digestive disorders or conditions that prevent normal nutrient absorption.
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...