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Cyclopeptide alkaloids from stems of Paliurus ramossisimus
1School of Pharmacy, College of Medicine, National Taiwan University, Taipei 100, Taiwan, Republic of China. shoeilee@ha.mc.ntu.edu.tw
Phytochemistry
|December 12, 2001
Abstract:
Three 13-membered cyclopeptide alkaloids, paliurines G, H and I, together with six known alkaloids, nummularine H, daechuine-S3, paliurines A-C and F, were isolated from the stem of Paliurus ramossisimus by a combination of centrifugal partition chromatography and preparative TLC. Their structures were characterized and established on the basis of spectral analysis. A preliminary study indicated that nummularine H could shorten the methohexital induced sleeping time.