Related Experiment Video
Updated: Jul 17, 2026

Stab Wound Injury of the Zebrafish Adult Telencephalon: A Method to Investigate Vertebrate Brain Neurogenesis and Regeneration
Published on: August 4, 2014
Cell proliferation without neurogenesis in adult primate neocortex
1Department of Neurobiology, Yale University School of Medicine, New Haven, CT 06510, USA.
Abstract:
A recent assertion that new neurons are continually added to the neocortex of adult macaque monkeys has profound implications for understanding the cellular mechanisms of higher cognitive functions. Here we searched for neurogenesis in adult macaques by using immunofluorescent triple labeling for the DNA-replication indicator, bromodeoxyuridine (BrdU), and neuronal and glial cell markers. Although numerous BrdU-labeled cells were distributed throughout the cerebral wall, including the neocortex, these were identified as nonneuronal cells; evidence for newly generated neurons was limited to the hippocampus and olfactory bulb. Thus, our results do not substantiate the claim of neurogenesis in normal adult primate neocortex.
More Related Videos
Related Concept Videos
Adult Stem Cells
Neurulation
Zygotic Development And Stem Cell Formation
Whole Body Regeneration
Nervous Tissue: Myelin
Schwann cells begin to form myelin sheaths around axons during fetal development. They wrap around a small...
Neurogenesis and Regeneration of Nervous Tissue

