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Alternariosis after liver transplantation
1Institut Clínic d' Infeccions i Inmunologia, IDIBAPS, Hospital Clínic, Universitat de Barcelona, Spain. nbenito@clinic.ub.es
Transplantation
|December 12, 2001
Summary
Alternaria fungal infections are a growing concern in organ transplant recipients. This review highlights a liver transplant case and discusses optimal antifungal treatments for alternariosis in these vulnerable patients.
Area of Science:
- Mycology
- Infectious Diseases
- Transplantation Medicine
Background:
- Alternaria, a saprophytic fungus, is an emerging human pathogen.
- Immunocompromised individuals, especially solid-organ transplant recipients, are at higher risk.
- Optimal antifungal therapy for alternariosis remains undefined.
Observation:
- A case of alternariosis following orthotopic liver transplantation is presented.
- Literature on Alternaria infections in organ transplant recipients is reviewed.
- Focus is placed on treatment strategies for these infections.
Findings:
- Combined surgical and medical management show promise for alternariosis.
- Limited case reports exist for liver transplant recipients with this infection.
- Further research is needed to establish definitive treatment protocols.
Implications:
- This case adds to the limited understanding of Alternaria infections post-liver transplant.
- The review emphasizes the need for defined antifungal treatment guidelines.
- Improved management strategies are crucial for improving outcomes in transplant patients.