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Heterotopic Auxiliary Rat Liver Transplantation With Flow-regulated Portal Vein Arterialization in Acute Hepatic Failure
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Alternariosis after liver transplantation

N Benito1, A Moreno, J Puig

  • 1Institut Clínic d' Infeccions i Inmunologia, IDIBAPS, Hospital Clínic, Universitat de Barcelona, Spain. nbenito@clinic.ub.es

Transplantation
|December 12, 2001
PubMed

Insights

Alternaria fungal infections are a growing concern in organ transplant recipients. This review highlights a liver transplant case and discusses optimal antifungal treatments for alternariosis in these vulnerable patients.

Area of Science:

  • Mycology
  • Infectious Diseases
  • Transplantation Medicine

Background:

  • Alternaria, a saprophytic fungus, is an emerging human pathogen.
  • Immunocompromised individuals, especially solid-organ transplant recipients, are at higher risk.
  • Optimal antifungal therapy for alternariosis remains undefined.

Observation:

  • A case of alternariosis following orthotopic liver transplantation is presented.
  • Literature on Alternaria infections in organ transplant recipients is reviewed.
  • Focus is placed on treatment strategies for these infections.

Findings:

  • Combined surgical and medical management show promise for alternariosis.
  • Limited case reports exist for liver transplant recipients with this infection.
  • Further research is needed to establish definitive treatment protocols.

Implications:

  • This case adds to the limited understanding of Alternaria infections post-liver transplant.
  • The review emphasizes the need for defined antifungal treatment guidelines.
  • Improved management strategies are crucial for improving outcomes in transplant patients.

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