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[Intracranial hypotension syndrome].

J Benito-León1, M A Reina, J Alvarez-Linera

  • 1Servicios de Neurología, Hospital General de Móstoles, Móstoles, Madrid, Spain. jbenitol@meditex.es

Neurologia (Barcelona, Spain)
|December 18, 2001
PubMed
Summary

Intracranial hypotension syndrome, caused by cerebrospinal fluid volume depletion, presents with orthostatic headaches and specific MRI findings. This review covers its clinical features, imaging, pathophysiology, and treatment.

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Area of Science:

  • Neurology
  • Radiology
  • Neurosurgery

Background:

  • Intracranial hypotension syndrome is a condition characterized by low cerebrospinal fluid pressure.
  • It can be primary or secondary to other conditions.
  • Cerebrospinal fluid volume depletion is the key factor determining its presentation.

Purpose of the Study:

  • To review the clinical and neuroimaging findings of intracranial hypotension syndrome.
  • To discuss the pathophysiology of the syndrome.
  • To outline the treatment options for intracranial hypotension syndrome.

Main Methods:

  • Review of clinical case studies and neuroimaging findings.
  • Analysis of the pathophysiology related to cerebrospinal fluid volume.
  • Synthesis of current treatment strategies.

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Main Results:

  • Intracranial hypotension syndrome presents with orthostatic headaches.
  • Magnetic resonance imaging typically shows diffuse dural gadolinium enhancement.
  • Subdural fluid collections and brain descent may also be observed.

Conclusions:

  • Understanding the clinical and imaging features is crucial for diagnosis.
  • Cerebrospinal fluid volume depletion underlies the syndrome's diverse manifestations.
  • Comprehensive review of pathophysiology and treatment is provided.