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Subtle prefrontal neuropathology in a pilot magnetic resonance spectroscopy study in patients with borderline
L T van Elst1, T Thiel, B Hesslinger
1Department of Psychiatry and Psychotherapy, Albert-Ludwigs-University, Freiburg, Germany. ludger_vanelst@psyallg.ukl.uni-freiburg.de
The Journal of Neuropsychiatry and Clinical Neurosciences
|December 19, 2001
Abstract:
The authors examined the brains of patients with borderline personality disorder (BPD) by using short echo time single voxel spectroscopy and found a significant 19% reduction of absolute N-acetylaspartate concentrations in the dorsolateral prefrontal cortex in BPD (P=0.01) compared with control subjects.