Related Experiment Video
Updated: Oct 2, 2026

Dynamic Contrast Enhanced Magnetic Resonance Imaging of an Orthotopic Pancreatic Cancer Mouse Model
Published on: April 18, 2015
Magnetic resonance imaging of the peritoneal cavity among peritoneal dialysis patients, using the dialysate as
Friedrich C Prischl1, Thomas Muhr1, Eva M Seiringer1
1*Third Department of Medicine/Nephrology and Second Department of Radiology, Krankenhaus der Barmherzigen Schwestern vom Hl. Kreuz, Wels, Austria.
Abstract:
The objectives of this study were to evaluate whether adequate observation of abdominal pathologic features related to peritoneal dialysis (PD) was possible with magnetic resonance imaging (MRI) under routine conditions, i.e., against the background of the dialysate and without contrast medium. For 16 male and seven female patients (mean age, 51.8 +/- 15.0 yr; mean duration of PD, 324 +/- 542 d), 25 peritoneal MRI studies were performed with the intraperitoneal dialysate as usual. Indications were symptoms or combinations of symptoms, such as leakage or abdominal wall edema (n = 3), bloody dialysate (n = 4), suspected herniation (n = 1), suspected ultrafiltration failure (n = 2), and abdominal pain (n = 5), or routine assessment after initiation of PD (n = 12). The MRI protocol, which was performed with a 1.0-T scanner, consisted of breath-hold, coronal and transverse, T2-weighted, half-Fourier single-shot turbo spin-echo sequences, using a standard body-array coil. MRI studies were well tolerated and successfully completed for all except two patients. Results indicated a leak along the catheter (n = 1), a leak in an umbilical hernia (n = 1), suspected leakage (n = 1), hernias (n = 5, in three patients), intraperitoneal adhesions (n = 5, in four patients), a ruptured ovarian cyst (n = 1), and pleural effusions (n = 4). Pathologic findings unrelated to PD or located extra-abdominally were observed in 19 of the 25 studies. The catheter tip position was easily identified for all patients. In conclusion, this first report on peritoneal MRI using only dialysate as the "contrast medium" indicates that MRI permits detailed observation of all relevant, PD-related, abdominal pathologic features against the dialysate background, thus avoiding system contamination (and thus the risk of peritonitis).
Insights
Magnetic resonance imaging (MRI) effectively visualizes abdominal issues in peritoneal dialysis (PD) patients using only dialysate. This non-contrast approach aids in diagnosing PD-related complications without system contamination.
Area of Science:
- Radiology
- Nephrology
- Medical Imaging
Background:
- Peritoneal dialysis (PD) requires monitoring for abdominal complications.
- Traditional imaging may involve contrast agents, posing risks.
- Evaluating PD-related pathology without contrast is desirable.
Purpose of the Study:
- To assess the utility of magnetic resonance imaging (MRI) for observing abdominal pathologies in peritoneal dialysis (PD) patients.
- To determine if MRI can detect PD-related issues using only the intraperitoneal dialysate as a background, without contrast agents.
Main Methods:
- 25 peritoneal MRI studies were conducted on 23 PD patients using a 1.0-T scanner.
- Standard T2-weighted, half-Fourier single-shot turbo spin-echo sequences were employed.
- Intraperitoneal dialysate was present as usual, serving as the sole contrast background.
Main Results:
- MRI successfully identified various PD-related findings, including catheter leaks, hernias, and intraperitoneal adhesions.
- The catheter tip position was clearly visualized in all patients.
- Non-PD related findings were also noted in a majority of studies.
Conclusions:
- Peritoneal MRI, utilizing dialysate as the contrast medium, allows for detailed observation of PD-related abdominal pathologies.
- This method avoids contrast agents, thereby eliminating the risk of peritonitis associated with system contamination.
- MRI is a valuable tool for routine assessment and diagnosis of complications in PD patients.
Related Concept Videos
Magnetic Resonance Imaging
Imaging Studies I: CT and MRI
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Peritoneal Dialysis I: Introduction and Procedure
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications
Peritoneal Dialysis III: Nursing Management
Imaging Studies IV: Magnetic Resonance Imaging

