Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

S/MARt DB: a database on scaffold/matrix attached regions.

Ines Liebich1, Jürgen Bode, Matthias Frisch

  • 1Research Group Bioinformatics, GBF, Mascheroder Weg 1, D-38124 Braunschweig, Germany. ili@gbf.de

Nucleic Acids Research
|December 26, 2001
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Optimization of family sizes in sets of crosses with a greedy allocation strategy based on automatic differentiation.

Frontiers in plant science·2026
Same author

Morphological and genetic diversity of <i>Beta maritima</i> populations across Europe and North Africa: a comprehensive review.

Frontiers in plant science·2026
Same author

Haplotype-based autoencoders can reduce the dataset dimension and estimate haplotype block effects in different crop species.

BMC bioinformatics·2025
Same author

Exploring the diversity of three Northern Atlantic sea beet populations.

Frontiers in plant science·2025
Same author

Crop wild relative populations of Beta vulgaris as source for genome-wide association mapping of complex traits.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·2025
Same author

Heterosis and hybrid breeding.

TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik·2025
Same journal

Correction to 'scSuperAnnotator: A platform for benchmarking comparison and visualizing automated cellular annotation methods for scRNA-seq data'.

Nucleic acids research·2026
Same journal

Correction to 'Differentiable partition function calculation for RNA'.

Nucleic acids research·2026
Same journal

Deployment of non-canonical splicing in tunicate genomes is mediated by divergent U2AF function and changing m6A modification in U1 and U6 snRNA.

Nucleic acids research·2026
Same journal

Bacillus subtilis DnaB forms multiple protein-protein interactions essential for DNA replication initiation.

Nucleic acids research·2026
Same journal

Multiple forms of protein-protein and DNA binding are exhibited by BrxC from the BREX phage restriction system.

Nucleic acids research·2026
Same journal

Biosynthesis of glycosylated 5-hydroxycytosine in the DNA of diverse viruses.

Nucleic acids research·2026
See all related articles

S/MARt DB is a relational database detailing scaffold/matrix attached regions (S/MARs) and nuclear matrix proteins. This resource aids research into chromosomal attachment to the nuclear scaffold.

Area of Science:

  • Molecular Biology
  • Genomics
  • Bioinformatics

Background:

  • Scaffold/matrix attached regions (S/MARs) are crucial DNA elements involved in organizing the genome within the nucleus.
  • Nuclear matrix proteins play a key role in the attachment of chromatin to the nuclear scaffold, influencing gene regulation.
  • Understanding S/MARs and associated proteins is essential for comprehending genome architecture and function.

Purpose of the Study:

  • To establish and maintain S/MARt DB, a comprehensive relational database for S/MARs and nuclear matrix proteins.
  • To integrate data from scientific literature and provide a web-based submission interface.
  • To facilitate research by linking S/MAR information with transcription factor binding data.

Main Methods:

  • Data extraction from peer-reviewed scientific publications.

Related Experiment Videos

  • Development of a relational database structure for S/MAR and protein information.
  • Implementation of a World Wide Web interface for data access and submission.

    • Main Results:

    • S/MARt DB provides a curated collection of S/MAR sequences and associated nuclear matrix proteins.
    • The database links S/MAR information with data from the TRANSFAC database, enhancing its utility.
    • A web interface is available for non-profit research access and direct data submission.

    Conclusions:

    • S/MARt DB serves as a valuable, freely accessible resource for researchers studying genome organization and nuclear architecture.
    • The database facilitates the study of chromosomal attachment mechanisms and their regulation.
    • Integration with transcription factor data enhances the potential for discovering regulatory roles of S/MARs.