Related Experiment Video
Updated: Oct 3, 2026

Social Defeat Stress Model for Adolescent C57BL/6 Male and Female Mice
Published on: March 15, 2024
Depression in adolescence
1Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota 55905, USA.
Abstract:
Major depression is a common mental health disorder in adolescents that predicts a significant risk for recurrence in adulthood. Suicide is the third most frequent cause of deaths in this age group, and depression is a significant risk factor for suicidal ideation and attempts. Risks for depression and suicidal ideation are reviewed, and subtypes of depression are discussed. Difficulties associated with identification of depression and suicidal ideation in adolescents and biologic therapies for adolescent depression are reviewed.
Related Concept Videos
Depression: Overview
Cognitive Development During Adolescence
Depressive Disorders: Etiology
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Erikson's Theory on Socioemotional Development during Adolescence
Depressive Disorders: MDD and Dysthymia
Self-Evaluation: Self-Enhancement and Self-Verification

