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Updated: Aug 17, 2026

A Murine Model of Cervical Spinal Cord Injury to Study Post-lesional Respiratory Neuroplasticity
Published on: May 28, 2014
Neurologic complications of respiratory disease
Douglas B Kirsch1, Ralph F Józefowicz
1Department of Neurology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA.
Abstract:
The respiratory system and the central nervous system are interconnected in a delicate balance; disorders in this equilibrium can have devastating consequences. Respiratory dysfunction, whether acute or chronic, may cause neurologic disease, including headache, encephalopathy, and in extreme cases, coma and death. This article will discuss abnormalities in ventilation and gas exchange, their subsequent pathophysiologic effects on the nervous system, and mechanisms of treatment for these disorders.
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