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Surgically treated Swyer-James syndrome
T Koyama1, H Osada, Y Kitanaka
1Department of Thoracic and Cardiovascular Surgery, St. Marianna University, Yokohama City Seibu Hospital, Yokohama, Japan.
The Japanese Journal of Thoracic and Cardiovascular Surgery : Official Publication of the Japanese Association for Thoracic Surgery = Nihon Kyobu Geka Gakkai Zasshi
|January 5, 2002
Summary
Swyer-James syndrome, a rare lung condition, involves emphysematous changes and fibrosis. Surgical intervention provided pathological insights into this condition, revealing alveolar destruction and peribronchiolar fibrosis.
Area of Science:
- Pulmonology
- Thoracic Surgery
- Pathology
Background:
- Swyer-James syndrome is a rare congenital or acquired condition affecting the lungs.
- Surgical pathological findings are infrequently reported due to conservative management approaches.
Observation:
- A 36-year-old woman with a history of recurrent bronchitis and pneumothorax presented with chest pain and dyspnea.
- Imaging revealed left upper lobe emphysema, bulla, and hypoplastic pulmonary arteries.
- The patient underwent left upper lobectomy for Swyer-James syndrome.
Findings:
- Pathological examination of the resected lobe showed significant emphysematous changes, including bulla formation and alveolar destruction.
- Peribronchiolar fibrosis was noted, consistent with chronic inflammation.
- Histological analysis did not reveal vascular abnormalities.
Implications:
- This case highlights the pathological features of Swyer-James syndrome, particularly emphysematous changes secondary to recurrent bronchiolitis.
- Surgical intervention can offer valuable insights into the underlying pathology of rare conditions.
- Understanding these findings may guide future management strategies for Swyer-James syndrome.