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Related Experiment Videos

Surgically treated Swyer-James syndrome.

T Koyama1, H Osada, Y Kitanaka

  • 1Department of Thoracic and Cardiovascular Surgery, St. Marianna University, Yokohama City Seibu Hospital, Yokohama, Japan.

The Japanese Journal of Thoracic and Cardiovascular Surgery : Official Publication of the Japanese Association for Thoracic Surgery = Nihon Kyobu Geka Gakkai Zasshi
|January 5, 2002
PubMed
Summary

Swyer-James syndrome, a rare lung condition, involves emphysematous changes and fibrosis. Surgical intervention provided pathological insights into this condition, revealing alveolar destruction and peribronchiolar fibrosis.

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Area of Science:

  • Pulmonology
  • Thoracic Surgery
  • Pathology

Background:

  • Swyer-James syndrome is a rare congenital or acquired condition affecting the lungs.
  • Surgical pathological findings are infrequently reported due to conservative management approaches.

Observation:

  • A 36-year-old woman with a history of recurrent bronchitis and pneumothorax presented with chest pain and dyspnea.
  • Imaging revealed left upper lobe emphysema, bulla, and hypoplastic pulmonary arteries.
  • The patient underwent left upper lobectomy for Swyer-James syndrome.

Findings:

  • Pathological examination of the resected lobe showed significant emphysematous changes, including bulla formation and alveolar destruction.
  • Peribronchiolar fibrosis was noted, consistent with chronic inflammation.

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  • Histological analysis did not reveal vascular abnormalities.

    • Implications:

    • This case highlights the pathological features of Swyer-James syndrome, particularly emphysematous changes secondary to recurrent bronchiolitis.
    • Surgical intervention can offer valuable insights into the underlying pathology of rare conditions.
    • Understanding these findings may guide future management strategies for Swyer-James syndrome.