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Updated: Aug 5, 2026

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
Published on: November 20, 2015
Preterm premature rupture of the membranes before viability
1Department of Obstetrics and Gynecology, University of Missouri-Kansas City School of Medicine, Saint Luke's Hospital, Kansas City, Missouri, USA. jyeast@saint-lukes.org
Abstract:
Although relatively uncommon, VPPROM remains a devastating complication of pregnancy. Current management options offer some hope of improved survival, but morbidity and mortality remain high. Counseling the patient and family following this diagnosis is challenging, and often requires input from both perinatal and neonatal staff. For those patients choosing expectant management who then reach viability, tertiary care should be considered to improve survival risks.
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