Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Mixed retrovirus infections.

L Evans1

  • 1Laboratory of Persistent Viral Diseases, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, MT 59840, USA.

Developments in Biologicals
|January 5, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

High-resolution geodetic velocities reveal role of weak faults in deformation of Tibetan Plateau.

Science (New York, N.Y.)·2026
Same author

IDF diabetes Atlas: A worldwide review of studies utilizing retinal photography to screen for diabetic retinopathy from 2017 to 2024 inclusive.

Diabetes research and clinical practice·2025
Same author

Concurrent nonavalent human papillomavirus (HPV) vaccination and immune stimulation with imiquimod to treat recalcitrant HPV-associated high grade vaginal intra-epithelial neoplasia.

Gynecologic oncology reports·2024
Same author

A Quantitative Method to Measure the Kinetics of Elemental Mercury Emissions From Black Shale (Nova Scotia, Canada).

Bulletin of environmental contamination and toxicology·2023
Same author

Computing committors via Mahalanobis diffusion maps with enhanced sampling data.

The Journal of chemical physics·2022
Same author

Meta-analysis of the outcomes of Trans Rectus Sheath Extra-Peritoneal Procedure (TREPP) for inguinal hernia. Author's reply.

Hernia : the journal of hernias and abdominal wall surgery·2022
Same journal

Review of Ebola virus infections in domestic animals.

Developments in biologicals·2013
Same journal

Ebola: facing a new transboundary animal disease?

Developments in biologicals·2013
Same journal

Opportunities in diagnostic and vaccine approaches to mitigate potential heartwater spreading and impact on the American mainland.

Developments in biologicals·2013
Same journal

Q fever diagnosis and control in domestic ruminants.

Developments in biologicals·2013
Same journal

Schmallenberg virus.

Developments in biologicals·2013
Same journal

Classical swine fever.

Developments in biologicals·2013
See all related articles

Viral pseudotyping, where one virus

Area of Science:

  • Virology
  • Molecular Biology

Background:

  • Mixed retrovirus infections can lead to viral pseudotyping.
  • This phenomenon involves encapsulating one virus' genome within another's protein coat, altering host range.

Purpose of the Study:

  • To investigate the implications of heterologous viral pseudotyping.
  • To assess potential risks associated with using non-human derived clinical reagents.

Main Methods:

  • Documented in vitro and in vivo studies of murine retroviral pseudotyping.
  • Analysis of heterologous species and viral family pseudotyping.

Main Results:

  • Pseudotyping can significantly alter viral replication and pathology.
  • Non-human retroviruses can infect human cells, raising concerns for clinical applications.

Related Experiment Videos

Conclusions:

  • Heterologous pseudotyping poses potential risks for clinical reagents derived from non-human systems.
  • Further in vivo studies are needed to understand the effects of heterologous pseudotyping on viral replication and pathology.