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[Malignant angiotropic lymphoma. With primary lung involvement].

C Glória1, N Diogo, H Vilela

  • 1Serviço de Pneumologia e Unidade de Cuidados Intensivos, Centro Hospitalar de Conde S. Januário, Macau.

Acta Medica Portuguesa
|January 5, 2002
PubMed
Summary

Angiotropic malignant lymphoma (AMLy) is a rare cancer where large lymphoid cells grow in blood vessels. This case highlights unusual primary lung involvement, presenting with dominant pulmonary symptoms.

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Area of Science:

  • Oncology
  • Hematology
  • Pathology

Background:

  • Angiotropic malignant lymphoma (AMLy) is a rare vascular neoplasm.
  • Typically, AMLy involves the central nervous system and skin.
  • Primary pulmonary involvement is exceptionally uncommon.

Observation:

  • This report details a rare case of AMLy with predominant pulmonary symptoms.
  • The patient presented with clinical manifestations primarily affecting the lungs.
  • Tumor cells were identified within the small pulmonary vessels.

Findings:

  • Immunoperoxidase stains confirmed tumor cells as B-phenotype lymphoid cells.
  • CD-20 positivity was observed, characteristic of this lymphoma subtype.
  • The findings support the diagnosis of pulmonary Angiotropic malignant lymphoma.

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Implications:

  • This case expands the understanding of AMLy's potential organ tropism.
  • It underscores the importance of considering AMLy in cases of unexplained pulmonary symptoms.
  • Further research into pulmonary AMLy could improve diagnostic and therapeutic strategies.