Related Experiment Video
Updated: Aug 12, 2026

Supramaximal Intensity Hypoxic Exercise and Vascular Function Assessment in Mice
Published on: March 15, 2019
Effects of equivalent sea-level and altitude training on VO2max and running performance
Abstract:
Twelve middle-distance runners, each having recently completed a competitive track season, were divided into two groups matched for maximal oxygen uptake (VO2max), 2-mile run time and age. Group 1 trained for 3 wk at Davis, PB = 760 mmHg, running 19.3 km/day at 75% of sea-level (SL) VO2max, while group 2 trained an equivalent distance at the same relative intensity at the US Air Force Academy (AFA), PB = 586 mmHg. The groups then exchanged sites and followed a training program of similar intensity to the group preceding it for an additional 3 wk. Periodic near exhaustive VO2max treadmill tests and 2-mile competitive time trials were completed. Initial 2-mile times at the AFA were 7.2% slower than SL control. Both groups demonstrated improved performance in the second trial at the AFA (chi = 2.0%), but mean postaltitude performance was unchanged from SL control. VO2max at the AFA was reduced initially 17.4% from SL control, but increased 2.6% after 20 days. However, postaltitude VO2max was 2.8% below SL control. It is concluded that there is no potentiating effect of hard endurance training at 2,300-m over equivalently severe SL training on SL VO2max or 2-mile performance time in already well conditioned middle-distance runners.
Related Concept Videos
Factors Affecting Respiration
Variation of Atmospheric Pressure
Assuming the air temperature is constant at a given altitude and that the ideal gas law of thermodynamics describes the atmosphere to a good approximation, one can find the variation of atmospheric pressure with height.
Let p(y) be the atmospheric pressure at...
Exercise and Cardiac Output
Sustained exercise increases the muscles' oxygen demand, which can be met...
Exercise and Cardiovascular Response
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Respiratory Volumes and Capacities
Introduction and Methods of Leveling

