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Proteomics: an holistic analysis of nature's proteins
1Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, UK. holger@glycob.ox.ac.uk
Current Opinion in Pharmacology
|January 5, 2002
Abstract:
Proteomics has matured to a technology platform way beyond two-dimensional gel electrophoresis, delivering on its promise to identify structure, function and cellular localization of all proteins expressed in a cell at a given time. Major achievements in the past year include mapping the proteome of human and microbial cells, improvements in two-dimensional gel electrophoresis and mass spectrometric analysis, and the development of protein arrays and biochips.