[Hyperkinesis in acute renal failure (clinico-pathomorphologic studies)]

Results of clinical and pathomorphological examinations of 74 patients with acute renal insufficiency are presented. Various forms of hyperkineses accompanying the grave course of acute renal insufficiency complicated with comatose state are described. The development of hyperkineses in patients with acute renal insufficiency is prognostically unfavourable. A substantial role in the pathogenesis of these neurological disturbances belongs to the water-electrolyte imbalance leading to development of diffuse microcirculatory and degenerative changes in all the divisions of the brain and the spinal cord. The pathomophological changes make it possible to differentiate a syndrome of metencephalic degeneration.