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Related Experiment Videos

Foix-Chavany-Marie syndrome.

M Y Ann1, O K Liu, Y L Wu

  • 1Department of Neurology, Taipei Municipal Chung-Hsin Hospital, ROC. annmy@gcn.net.tw

Zhonghua Yi Xue Za Zhi = Chinese Medical Journal; Free China Ed
|January 5, 2002
PubMed
Summary
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Foix-Chavany-Marie syndrome (FCMS) involves facial and swallowing paralysis. This case highlights FCMS resulting from multiple strokes affecting brain regions controlling speech and movement.

Area of Science:

  • Neurology
  • Neuroimaging
  • Cerebrovascular Disease

Background:

  • Foix-Chavany-Marie syndrome (FCMS) is a rare neurological disorder characterized by suprabulbar palsy.
  • It presents with anarthria and paralysis of facial, lingual, pharyngeal, and masticatory muscles, with a dissociation between automatic and voluntary movements.
  • The cortico-subcortial type of suprabulbar palsy, FCMS, is often linked to lesions in the opercular regions.

Observation:

  • A 64-year-old male presented with acute speechlessness.
  • Clinical examination revealed classic signs of FCMS.
  • Cranial MRI identified a right opercular lesion and multiple bilateral lacunar infarcts.

Findings:

  • Hexamethylen-propylene amine oxime (HMPAO) brain SPECT demonstrated hypoperfusion in bilateral opercular areas, more pronounced on the right.

Related Experiment Videos

  • The findings suggest FCMS in this patient resulted from multiple cerebrovascular insults affecting bilateral cortico-subcortial opercular regions.
  • Stroke in the opercular region is the most common etiology for FCMS.

    • Implications:

    • This case underscores the role of multiple cerebrovascular events in the pathogenesis of FCMS.
    • Neuroimaging techniques like MRI and SPECT are crucial for diagnosing FCMS and identifying underlying vascular causes.
    • Understanding the specific vascular territories affected can aid in predicting prognosis and management strategies for FCMS.