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Updated: Jul 26, 2026

Non-Invasive Model of Neuropathogenic Escherichia coli Infection in the Neonatal Rat
Published on: October 29, 2014
Septicemia due to multiple biotypes of Escherichia coli
1Department of Obstetrics and Gynecology, The Genesee Hospital, Rochester, New York, USA.
Background:
Polymicrobial bacteremias with different biotypes of the same organism have not been reported as a cause of bacteremia in any patient.
Case:
A 37-year-old gravida had a cesarean delivery performed after a failed vacuum extraction. On the second postoperative day, she developed a septicemia with temperature to 39.4C. Three different biotypes of Escherichia coli with different antibiotic susceptibilities were isolated from her blood. A fourth biotype was isolated from the urinary and genital tracts; therefore, the source of her bacteremia was not apparent. She was treated successfully with cefoxitin and gentamicin.
Conclusion:
Accurate selection of colonies from microbiological isolation plates allowed identification of four different E. coli biotypes (three in the blood) from a bacteremic patient. Rapid identification of antibiotic susceptibility is important in such patients.
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