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Updated: Jun 26, 2026

Murine Model of Allergen Induced Asthma
Published on: May 14, 2012
Do air cleaners make a difference in treating allergic disease in homes?
1State University of New York at Buffalo and Buffalo Medical Group, Williamsville 14221, USA. rreis3333@aol.com
Learning Objectives:
The purpose of this review is to objectively critique available data regarding the clinical benefits of room air cleaners and to provide physicians and patients with a reasonable recommendation of their utility in treatment of inhalant allergic disease.
Date Sources:
Data were obtained from published studies and reviews.
Study Selection:
The specific reviewed studies met the following criteria: 1) selection of patients with clinical allergic disease confirmed by detection of allergen-specific immunoglobulin E; 2) use of an effective air filter; 3) clinical and laboratory evaluation of results; and 4) measurement of the results of air filtration on environmental allergen or airborne particulate levels. The studies were conducted in a double-blind manner. Conclusions of two previous reviews are also incorporated in this paper.
Results:
The results of the published studies and summary reviews show minimal, if any, effectiveness of room air cleaners in treatment of allergic respiratory disease.
Conclusions:
Room air cleaners should not be recommended for people with inhalant allergic disease.
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