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The lectin-binding properties of six generations of mannose-functionalized dendrimers
Eric K Woller1, Mary J Cloninger
1Department of Chemistry and Biochemistry, 108 Gaines Hall, Montana State University, Bozeman, Montana 59717, USA.
Organic Letters
|January 5, 2002
Abstract:
[structure: see text] First- through sixth-generation PAMAM dendrimers have been functionalized with mannose residues. Characterization with MALDI-TOF MS and (1)H NMR is reported. Different binding enhancements consistent with monovalent interaction, glycoside clustering, and multivalent binding are observed for different generations of dendrimers.