Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Confocal Fluorescence Microscopy01:16

Confocal Fluorescence Microscopy

Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Rapid Identification of Pathogens01:25

Rapid Identification of Pathogens

MALDI-TOF MS has transformed clinical microbiology by offering a rapid and reliable method for pathogen identification. The traditional approach to microbial identification typically involves time-consuming culture techniques and biochemical tests, which can delay the initiation of appropriate antimicrobial therapy. MALDI-TOF MS avoids these delays by using characteristic ribosomal protein mass patterns of microbial cells, enabling accurate species-level identification within minutes.Principle...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Unconventional Field-Induced Spin Gap in an S=1/2 Chiral Staggered Chain.

Physical review letters·2019
Same author

FISH-negative, cytogenetically cryptic acute promyelocytic leukemia.

Blood cancer journal·2015
Same author

Prompt all-trans retinoic acid administration and early death in acute promyelocytic leukemia: what does the evidence say?

Leukemia·2014
Same author

Hepatocellular carcinoma with metastasis to the spleen in a Holstein cow.

Veterinary pathology·2005
Same author

Multiple congenital malformation in a Holstein calf.

Journal of comparative pathology·2003
Same author

Clinical evaluation of an international static image-based telepathology service.

Human pathology·2002

Related Experiment Video

Updated: Jul 24, 2026

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
09:37

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

Published on: August 18, 2022

Telehematopathology in a clinical consultative practice.

S I Fisher1, M A Nandedkar, B H Williams

  • 1Department of Hematopathology, The Armed Forces Institute of Pathology, Washington, DC20306-6000, USA.

Human Pathology
|January 5, 2002
PubMed
Summary

This study examined the use of telehematopathology in consultative practice by analyzing 60 cases reviewed between 1995 and 2000. The authors found that telepathology diagnoses matched traditional glass slide reviews in 91% of cases with follow-up data. Image quality varied, with low-power images most commonly rated poorly. Factors like incomplete immunoperoxidase stains and lack of ancillary data affected accuracy. The study suggests that telehematopathology can be effective when technical and data requirements are met. Recommendations include optimizing image transmission and including clinical and laboratory data to improve outcomes. The authors conclude that telehematopathology has significant potential for subspecialty consultation.

Keywords:
telepathology accuracyhematopathology consultationdigital pathologyremote medical diagnosis

Frequently Asked Questions

More Related Videos

Skin Biopsy for Diagnosing Discoid Lupus Erythematosus
05:44

Skin Biopsy for Diagnosing Discoid Lupus Erythematosus

Published on: June 10, 2025

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:39

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

Related Experiment Videos

Last Updated: Jul 24, 2026

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
09:37

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

Published on: August 18, 2022

Skin Biopsy for Diagnosing Discoid Lupus Erythematosus
05:44

Skin Biopsy for Diagnosing Discoid Lupus Erythematosus

Published on: June 10, 2025

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
05:39

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

Area of Science:

  • Digital pathology in clinical diagnostics
  • Hematopathology consultative practices
  • Telemedicine in medical specialty services

Background:

Consultative hematopathology often requires subspecialist expertise, which may be geographically limited. Prior research has shown that telepathology can bridge this gap by enabling remote diagnosis. However, the diagnostic accuracy of telehematopathology remains understudied. This paper addresses a gap in the literature by examining the performance of telehematopathology in real-world clinical settings. The study focuses on a specific dataset of consultative cases to evaluate the feasibility of telepathology in hematopathology. No prior work had resolved the diagnostic concordance rates in this context. The authors aim to clarify how telehematopathology compares to traditional glass slide review. They also explore factors that may influence diagnostic accuracy in remote consultations. This study contributes to understanding the practical limitations and potential of telepathology in hematopathology.

Purpose Of The Study:

The study aimed to evaluate the diagnostic accuracy of telehematopathology in a clinical consultative setting. It focused on a specific cohort of 60 cases reviewed between 1995 and 2000. The goal was to assess how well remote diagnosis matched traditional methods. The authors sought to identify factors that could influence diagnostic outcomes. They also aimed to provide practical recommendations for improving telepathology consultations. The motivation was to determine whether telehematopathology could be a reliable alternative to in-person consultation. The study sought to measure diagnostic concordance rates and image quality. It also aimed to highlight challenges in specimen preparation and data transmission.

Main Methods:

The study analyzed 60 telepathology cases sent to a hematopathology department between 1995 and 2000. Cases were collected from multiple sectors including academic, private, military, and federal institutions. The authors reviewed patient demographics, specimen types, and diagnostic outcomes. They categorized cases by site of origin and type of specimen. Image quality was assessed using a three-tier rating system. The concordance rate was calculated by comparing telepathology diagnoses to follow-up glass slide reviews. Ancillary data availability was also evaluated. The authors identified factors that may have influenced diagnostic accuracy in remote consultations.

Main Results:

The study found a 91% concordance rate between telehematopathology diagnoses and follow-up glass slide reviews. Out of 32 cases with available follow-up, 29 matched and 3 did not. Image quality varied, with 49% rated as very good or good. Poor image quality was linked to suboptimal resolution and transmission issues. Low-power images were most commonly rated poorly. Ancillary data availability was limited in some cases. Immunoperoxidase stains and molecular data were often missing. The study identified several factors affecting diagnostic accuracy. These findings suggest that telehematopathology can achieve high diagnostic accuracy under optimal conditions.

Conclusions:

The authors propose that telehematopathology is a viable solution for subspecialty consultation in hematopathology. They emphasize the need for high-quality image transmission and ancillary data availability. The study suggests that telepathology can achieve high diagnostic concordance rates. However, poor image quality and incomplete data may reduce accuracy. The authors recommend optimizing technical equipment and training for telepathology consultations. They also suggest including clinical and laboratory data to improve diagnostic outcomes. The study concludes that telehematopathology has significant potential in global and national consultation settings. It may become a powerful tool when combined with modern diagnostic technologies.

The study found a 91% concordance rate between telehematopathology diagnoses and follow-up glass slide reviews.

Poor image quality, incomplete immunoperoxidase stains, and lack of ancillary data were linked to lower diagnostic accuracy.

Low-power images were most commonly rated as poor due to suboptimal resolution and transmission quality.

Ancillary data such as immunoperoxidase stains and molecular data were often missing, affecting diagnostic accuracy.

Follow-up glass slide reviews were available for 32 of the 60 cases analyzed in the study.

The authors suggested optimizing image transmission, including clinical data, and ensuring availability of ancillary studies.