Neuroprotection is unlikely to be effective in humans using current trial designs: an opposing view

Impact of central adjudication of the score on the modified Rankin Scale in an international, randomized, acute stroke trial.

European stroke journal·2025

Cerebral Small Vessel Disease and Infarct Growth in Acute Ischemic Stroke Treated with Intravenous Thrombolysis.

Translational stroke research·2024

Xanthine oxidase inhibition and white matter hyperintensity progression following ischaemic stroke and transient ischaemic attack (XILO-FIST): a multicentre, double-blinded, randomised, placebo-controlled trial.

EClinicalMedicine·2023

Safety and Outcomes of Thrombectomy in Ischemic Stroke With vs Without IV Thrombolysis.

Neurology·2021

Timing of initiation of oral anticoagulants in patients with acute ischemic stroke and atrial fibrillation comparing posterior and anterior circulation strokes.

European stroke journal·2021

The SITS Open Study: A Prospective, Open Label Blinded Evaluation Study of Thrombectomy in Clinical Practice.

Stroke·2021

Social Determinants of Health in Early to Mid-Adulthood and Risk of Early-Onset Stroke.

Stroke·2026

Utility-Weighted Analysis of the Modified Rankin Scale: An Updated Review of Methods, Challenges, and Future Directions.

Stroke·2026

Role of Clinical Trials in Implementation Science and Organization Change: An Overview of Cluster, Stepped-Wedge, and Hybrid Effectiveness-Implementation Studies.

Stroke·2026

Immune Checkpoint B7-H3 Inhibition Reprograms Acute Neuroinflammation and Protects the Brain After Acute Ischemic Stroke.

Stroke·2026

Intervention Design for Individual Behavior Change in Stroke Prevention Trials.

Stroke·2026

Cilostazol Treatment for Intracerebral Hemorrhage: Targeting Dural Lymphatics.

Stroke·2026

Systemic inflammatory indices primarily reflect tumor burden rather than independently predict prognosis in HPV-associated oropharyngeal squamous cell carcinoma.

Acta oto-laryngologica·2026

Genetically Predicted Gene Expression and Circulating Metabolites Associated with Cervical High-Grade Squamous Intraepithelial Lesion: A Mendelian Randomization Study.

International journal of women's health·2026

Cytological biomarkers and risk of malignancy in indeterminate thyroid nodules: a systematic review and meta-analysis.

Endocrine oncology (Bristol, England)·2026

Evaluation of CD10 expression in prostate adenocarcinoma and its clinic-pathological correlation at tertiary care hospital.

Bioinformation·2026

Endometriosis as a Silent Emerging Malignant Threat in Young Women: A Case Report of Rare Rapid Transformation of Abdominal Wall Endometriosis Into Mixed High-Grade Serous and Clear Cell Carcinoma One Year Following Cesarean Section.

Cureus·2026

Salivary cathelicidin LL-37 as a non-invasive biomarker for oral cancer detection.

Bioinformation·2026

Related Experiment Videos

Neuroprotection is unlikely to be effective in humans using current trial designs: an opposing view

Related Concept Videos

Impact of central adjudication of the score on the modified Rankin Scale in an international, randomized, acute stroke trial.

Cerebral Small Vessel Disease and Infarct Growth in Acute Ischemic Stroke Treated with Intravenous Thrombolysis.

Xanthine oxidase inhibition and white matter hyperintensity progression following ischaemic stroke and transient ischaemic attack (XILO-FIST): a multicentre, double-blinded, randomised, placebo-controlled trial.

Safety and Outcomes of Thrombectomy in Ischemic Stroke With vs Without IV Thrombolysis.

Timing of initiation of oral anticoagulants in patients with acute ischemic stroke and atrial fibrillation comparing posterior and anterior circulation strokes.

The SITS Open Study: A Prospective, Open Label Blinded Evaluation Study of Thrombectomy in Clinical Practice.

Social Determinants of Health in Early to Mid-Adulthood and Risk of Early-Onset Stroke.

Utility-Weighted Analysis of the Modified Rankin Scale: An Updated Review of Methods, Challenges, and Future Directions.

Role of Clinical Trials in Implementation Science and Organization Change: An Overview of Cluster, Stepped-Wedge, and Hybrid Effectiveness-Implementation Studies.

Immune Checkpoint B7-H3 Inhibition Reprograms Acute Neuroinflammation and Protects the Brain After Acute Ischemic Stroke.

Intervention Design for Individual Behavior Change in Stroke Prevention Trials.

Cilostazol Treatment for Intracerebral Hemorrhage: Targeting Dural Lymphatics.

Systemic inflammatory indices primarily reflect tumor burden rather than independently predict prognosis in HPV-associated oropharyngeal squamous cell carcinoma.

Genetically Predicted Gene Expression and Circulating Metabolites Associated with Cervical High-Grade Squamous Intraepithelial Lesion: A Mendelian Randomization Study.

Cytological biomarkers and risk of malignancy in indeterminate thyroid nodules: a systematic review and meta-analysis.

Evaluation of CD10 expression in prostate adenocarcinoma and its clinic-pathological correlation at tertiary care hospital.

Endometriosis as a Silent Emerging Malignant Threat in Young Women: A Case Report of Rare Rapid Transformation of Abdominal Wall Endometriosis Into Mixed High-Grade Serous and Clear Cell Carcinoma One Year Following Cesarean Section.

Salivary cathelicidin LL-37 as a non-invasive biomarker for oral cancer detection.

Related Experiment Videos

Neuroprotection is unlikely to be effective in humans using current trial designs: an opposing view

Related Concept Videos

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