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Enteric Bacterial Invasion Of Intestinal Epithelial Cells In Vitro Is Dramatically Enhanced Using a Vertical Diffusion Chamber Model
10:52

Enteric Bacterial Invasion Of Intestinal Epithelial Cells In Vitro Is Dramatically Enhanced Using a Vertical Diffusion Chamber Model

Published on: October 22, 2013

Gastrointestinal infections

G W Procop1

  • 1Department of Clinical Microbiology, Cleveland Clinic Foundation, Cleveland, Ohio, USA. procopg@ccf.org

Infectious Disease Clinics of North America
|January 10, 2002
PubMed

Insights

Public health advances have decreased some enteric diseases, but new pathogens emerge. Judicious use of microbiologic assays, guided by patient factors, is crucial for accurate diagnosis and cost control.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Public Health

Background:

  • Despite public health advancements, enteric diseases remain a significant concern.
  • Emerging and newly discovered pathogens contribute to the burden of enteric infections.
  • Pathogenic agents include diverse bacteria, viruses, and parasites.

Purpose of the Study:

  • To emphasize the importance of judicious use of microbiologic assays for enteric pathogens.
  • To highlight factors influencing the selection of appropriate diagnostic tests.
  • To advocate for cost-effective diagnostic strategies in clinical practice.

Main Methods:

  • Review of current knowledge on enteric pathogens and diagnostic methods.
  • Analysis of factors influencing etiologic agent identification (age, season, travel, symptoms).
  • Emphasis on the role of clinical presentation in guiding diagnostic test selection.

Main Results:

  • Microbiologic assays are essential for detecting and confirming enteric pathogens.
  • Non-judicious testing leads to escalating healthcare costs.
  • Clinical information is vital for selecting the most relevant diagnostic assays.

Conclusions:

  • Strategic application of microbiologic assays is recommended for diagnosing enteric diseases.
  • Clinical clues should guide the selection of diagnostic tests to ensure efficiency and accuracy.
  • Judicious testing aids in confirming or excluding suspected infectious agents, optimizing patient care.

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