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High-throughput structural proteomics using x-rays
1Astex Technology, Cambridge, UK. h.jhoti@astex-technology.com
Trends in Biotechnology
|January 10, 2002
Abstract:
Following the recent sequencing of the human genome, the focus has shifted from the DNA level to the protein level, with the goal of elucidating function. Technical developments in x-ray crystallography mean that the crystal structures of these new proteins can now been determined at an unprecedented rate, which assists in functional analysis and rational drug-design programmes.