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Updated: Oct 3, 2026
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Standardized Rat Coronary Ring Preparation and Real-Time Recording of Dynamic Tension Changes Along Vessel Diameter
Published on: June 16, 2022
Effect of amylin on the tone of rat aorta ring preparation
G V Luk'yantseva1, I Y Sergeev, G N Kopylova
1Department of Human and Animal Physiology, Biological Faculty, M. V. Lomonosov Moscow State University.
Bulletin of Experimental Biology and Medicine
|January 10, 2002
Abstract:
Amylin (10(-10)M) induced relaxation of norepinephrine-precontracted rat aortic rings by more than 50%. This effect was preserved after blockade of NO-synthase and even after denudation of the vessel. Thus amylin-induced vasodilation is an endothelium-independent process not mediated by NO.
