Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Giant evoked potentials].

M M Baez Martín1, L Gómez Fernández, I Cabrera Abreu

  • 1Laboratorio de Neurofisiología Clínica; Centro Internacional de Restauración Neurológica (CIREN), La Habana, 11300, Cuba. mariajo@infomed.sld.cu

Revista De Neurologia
|January 11, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pedigree-based assessment of genetic structure and disease-associated variants in friesian horses in Brazil.

Journal of equine veterinary science·2026
Same author

Peripapillary intrachoroidal cavitation.

Archivos de la Sociedad Espanola de Oftalmologia·2025
Same author

Lung disease in rheumatoid arthritis: Results from a national cohort.

Pulmonology·2023
Same author

Effects of two alveolar recruitment manoeuvres (sustained inflation and stepwise) followed by positive end-expiratory pressure on cardiac output (measured with lithium dilution), invasive blood pressure and arterial oxygen tension in isoflurane-anaesthetised goats.

Research in veterinary science·2022
Same author

Exposure of humans to the zoonotic nematode <i>Dirofilaria immitis</i> in Northern Portugal.

Epidemiology and infection·2019
Same author

Phosphorus fractionation in sediments of tropical semiarid reservoirs.

The Science of the total environment·2018
Same journal

The Correlation Between and Variability of Three Balance Scales in the Assessment of Balance Function in Patients With Ataxia.

Revista de neurologia·2026
Same journal

Surgical Treatment of an Aneurysm in the Subacute Stage of Hemorrhagic Moyamoya Disease: Aneurysm Resection Combined With STA-MCA Bypass: A Case Report.

Revista de neurologia·2026
Same journal

Mapping the Evidence: Central Sleep Apnea Syndromes During Sleep and Stroke-A Scoping Review.

Revista de neurologia·2026
Same journal

Developmental and Epileptic Encephalopathy Due to a Novel <i>ARHGEF9</i> Deletion Variant: Case Series of Two Siblings.

Revista de neurologia·2026
Same journal

P300 Event-Related Potentials as Cognitive Biomarkers in Neurological and Neuropsychiatric Disorders: A Systematic Review.

Revista de neurologia·2026
Same journal

[Effectiveness and Risk of Recurrence of Pulsed Radiofrequency in Trigeminal Neuralgia and Chronic Cluster Headache].

Revista de neurologia·2026
See all related articles

Giant evoked potentials, characterized by large amplitude cortical responses, indicate a state of cortical hyperexcitability. These electrophysiological findings can stem from various neurological conditions, including epilepsy and myoclonus.

Area of Science:

  • Neurophysiology
  • Clinical Neurology
  • Electrophysiology

Background:

  • Giant evoked potentials are high-amplitude cortical responses observed across diverse neurological conditions.
  • These potentials are often associated with cortical myoclonic conditions like epilepsy and myoclonus of toxic, infectious, or postanoxic origin.
  • They have also been documented in focal hemisphere lesions and corticobasal degeneration.

Observation:

  • This study analyzed 6 patients (ages 2-22) using multimodal evoked potentials, EEG, and imaging.
  • Giant somatosensory potentials were observed in patients with evident myoclonia.
  • High-amplitude visual evoked potentials were noted in patients with or without myoclonia.

Findings:

  • Giant evoked potentials are a marker of cortical hyperexcitability.

Related Experiment Videos

  • The underlying causes of this hyperexcitability are varied, encompassing conditions like epilepsy and myoclonus.
  • Electrophysiological studies are crucial for identifying these responses and guiding diagnosis.

    • Implications:

    • Understanding the mechanisms behind giant evoked potentials aids in diagnosing and managing diverse neurological disorders.
    • Cortical hyperexcitability, as indicated by these potentials, highlights a common pathophysiological pathway.
    • Further research into the specific triggers and management of cortical hyperexcitability is warranted.