Related Experiment Videos
[Giant evoked potentials]
M M Baez Martín1, L Gómez Fernández, I Cabrera Abreu
1Laboratorio de Neurofisiología Clínica; Centro Internacional de Restauración Neurológica (CIREN), La Habana, 11300, Cuba. mariajo@infomed.sld.cu
Introduction:
There are many, diverse nosological entities with the common factor of the genesis of cortical evoked potentials of great amplitude, commonly known as giant evoked potentials. In most cases they are conditions with the common clinical condition of myoclonic of cortical origin, such as progressive myoclonic epilepsy, generalized idiopathic epilepsy, myoclonias of toxic, infectious or postanoxic origin. Giant potentials have been shown both in studies of focal hemisphere lesions and in some cases of patients with corticobasal degeneration.
Objective:
The aim of this paper was to show, by presenting interesting cases, some of the conditions mentioned and to review some concepts concerning the mechanisms which may be involved in the production of these electrophysiological responses.
Patients And Methods:
We studied 6 patients aged between 2 and 22 years, in whom multimodal evoked potentials, electroencephalograms and imaging studies had been done.
Results:
Giant somatosensory potentials were shown in the patients with obvious myoclonia. Visual potentials of great amplitude were common to the other patients presented, with or without myoclonia.
Conclusion:
Giant evoked potentials respond to a state of cortical hyperexcitability which may have various causes.