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Related Experiment Videos

Cadherin-mediated cell sorting not determined by binding or adhesion specificity.

Carien M Niessen1, Barry M Gumbiner

  • 1Cellular Biochemistry and Biophysics Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

The Journal of Cell Biology
|January 16, 2002
PubMed
Summary

Cadherin molecules, crucial for tissue boundaries, show promiscuous binding, not specific adhesion. Cell sorting is not determined by cadherin binding specificity, suggesting other mechanisms are involved.

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