Related Experiment Video
Updated: Oct 2, 2026

Cerebral Blood Flow-Based Resting State Functional Connectivity of the Human Brain using Optical Diffuse Correlation Spectroscopy
Published on: May 27, 2020
Localized 2D correlation spectroscopy in human brain at 3 T
Anne Ziegler1, Brigitte Gillet, Jean-Claude Beloeil
1Unité mixte INSERM, Université J. Fourier U438 'RMN Bioclinique', LRC CEA, CHU pavillon B, BP 217, 38043 Cedex 9, Grenoble, France. anne.ziegler@ujf-grenoble.fr
Abstract:
The purpose of this study was to acquire a localized 2D (two-dimensional) 1H correlation spectrum, in a volume of interest reasonably small, and within an experiment time compatible with clinical applications. A modified PRESS technique has been used. The last 180 degrees pulse of the PRESS sequence has been converted into a 90 degrees pulse for both refocusing and coherence transfer. 2D correlation spectroscopy was performed on healthy volunteers in a clinical magnet, at 3 T, within 34 min, for a voxel size of 27 cm3. This result makes it possible to consider clinical applications.
More Related Videos
Related Concept Videos
2D NMR: Overview of Homonuclear Correlation Techniques
COSY90 is the standard two-dimensional (2D) COSY experiment that...
2D NMR: Overview of Heteronuclear Correlation Techniques
2D NMR: Heteronuclear Single-Quantum Correlation Spectroscopy (HSQC)
2D NMR: Homonuclear Correlation Spectroscopy (COSY)

