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Published on: September 8, 2017
Successful treatment of metastatic hormone-refractory prostate cancer with malignant pericardial tamponade using
Brandon M Hayes-Lattin1, Peter A Kovach, W David Henner
1Oregon Health and Science University, Portland, Oregon 97201, USA.
Abstract:
Reports of malignant pericardial effusion due to adenocarcinoma of the prostate are few and describe only patients with hormone-naive disease. We report a case of malignant pleural and pericardial effusions due to metastatic hormone-refractory prostate cancer. Despite presenting with pericardial tamponade, this patient was successfully treated with pericardiocentesis and intrapericardial methylprednisolone and cisplatin, followed by a course of intravenous docetaxel. The patient was alive and free of disease-related symptoms nearly 2 years later. This case suggests that patients with pericardial tamponade due to hormone-refractory prostate cancer do not have a uniformly dismal prognosis and should be considered for aggressive treatment.
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