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[Pathomorphologic changes in calves with ruminal acidosis for fattening]
Summary
Massive acute and subacute rumen acidosis in calves, caused by abrupt feeding changes, led to severe organ damage. Necrotic and hemorrhagic lesions were observed throughout the digestive tract and associated organs.
Area of Science:
- Veterinary Pathology
- Ruminant Medicine
- Animal Nutrition
Context:
- Rumen acidosis is a significant metabolic disorder in feedlot cattle.
- Abrupt dietary shifts are a primary trigger for acute and subacute rumen acidosis.
- Understanding the pathological consequences is crucial for disease management.
Purpose:
- To investigate the comprehensive morphologic alterations in organs of calves suffering from acute and subacute rumen acidosis.
- To document gross and histological changes associated with this condition.
Summary:
- Gross examination revealed hemorrhagic and necrotic foci in the rumen, hyperemia and hemorrhages in the omasum and reticulum, and ulcers in the abomasum.
- Enlarged forestomach lymph nodes, liver, and kidney edema were noted.
- Histological findings included necrotic inflammation, exudate, leukocyte infiltration, hyphae, thrombuses, arteritis in the rumen, mucosal desquamation in the omasum/reticulum, and necrotic foci/edema/infiltrations in the abomasum.
- Degenerative changes, hyperemia, fatty infiltration, and interstitial activation were observed in other organs like the thyroid, pancreas, kidneys, liver, heart, and adrenal glands.
- Elevated alkaline phosphatase activity was detected in the kidneys, adrenal glands, and liver.
Impact:
- Provides detailed pathological data on rumen acidosis in calves, aiding in diagnosis and treatment strategies.
- Highlights the systemic effects of rumen acidosis beyond the gastrointestinal tract.
- Informs nutritional management practices to prevent feed-related metabolic diseases in cattle.