Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Kawasaki disease: an update.

Abraham Gedalia1

  • 1Departments of Pediatrics, LSU Health Sciences Center and Children's Hospital, 1542 Tulane Avenue, T8-1, New Orleans, LA 70112, USA. a61543@pol.net

Current Rheumatology Reports
|January 19, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Kawasaki Disease: an Update.

Current rheumatology reports·2020
Same author

Refractory Pain and Swelling of the Left Wrist in a 7-Year-Old Female.

Clinical pediatrics·2019
Same author

6-Year-Old With Severe Hypertension.

Clinical pediatrics·2017
Same author

A 19-Year-Old Woman With Increased Urinary Frequency, Abdominal and Back Pain.

Clinical pediatrics·2016
Same author

Disability in Children and Adolescents With Irritable Bowel Syndrome and/or Fibromyalgia.

Journal of pediatric gastroenterology and nutrition·2015
Same author

Severe Musculoskeletal Pain in a Patient With Systemic Lupus Erythematosus.

Clinical pediatrics·2015

Kawasaki disease (KD) is an enigmatic illness with an unknown cause, though infectious agents are suspected. Current treatments like aspirin and IVIG improve outcomes, but research is ongoing for non-responsive cases.

Area of Science:

  • Pediatrics
  • Immunology
  • Infectious Diseases

Background:

  • Kawasaki disease (KD) was first described over 30 years ago, with diagnostic criteria remaining largely unchanged.
  • The etiology of KD is currently unknown, though infectious agents are implicated.
  • Coronary artery aneurysms and associated mortality are significant concerns in KD patients.

Purpose of the Study:

  • To review the current understanding of Kawasaki disease.
  • To discuss advances in KD management, including aspirin and IVIG.
  • To highlight areas requiring further research, such as treatment resistance and long-term outcomes.

Main Methods:

  • Review of existing literature on Kawasaki disease.
  • Analysis of clinical observations and epidemiological data.

Related Experiment Videos

  • Discussion of current therapeutic strategies and their efficacy.

    • Main Results:

    • Aspirin and intravenous immunoglobulin (IVIG) have significantly reduced coronary artery aneurysms and mortality.
    • A subset of KD patients exhibit resistance to IVIG treatment.
    • Pulse steroid therapy shows potential benefit for severe, IVIG-resistant KD.

    Conclusions:

    • While IVIG and aspirin are effective, management of IVIG-resistant KD requires further investigation.
    • The role of steroids and other anti-inflammatory agents in KD treatment needs clarification.
    • Future research should focus on identifying the cause, optimizing treatment, and predicting long-term outcomes of KD.