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Published on: July 19, 2018
Chronic fatigue in long-term peritoneal dialysis patients
W K Chang1, K Y Hung, J W Huang
1Department of Internal Medicine, Jen-Ai Municipal Hospital, Taipei, Taiwan, ROC.
American Journal of Nephrology
|January 19, 2002
Summary
Dialysis adequacy significantly impacts chronic fatigue in peritoneal dialysis patients. Weekly creatinine clearance showed a stronger correlation with fatigue than Kt/V(urea), highlighting its importance in managing patient well-being.
Area of Science:
- Nephrology
- Clinical Medicine
- Patient Care
Background:
- Fatigue is a prevalent and debilitating symptom for patients undergoing long-term dialysis.
- Understanding the clinical factors contributing to fatigue in peritoneal dialysis (PD) patients is crucial for improving quality of life.
Purpose of the Study:
- To investigate clinical factors associated with the development of fatigue in PD patients.
- To examine the relationship between total solute clearance (TSC) and fatigue symptoms in this population.
Main Methods:
- A cross-sectional study involving 64 PD patients (31 CAPD, 33 CCPD) was conducted.
- Patients were categorized by fatigue scores (mild, moderate, severe) using a 14-item questionnaire.
- Clinical characteristics, dialysis adequacy (Kt/V(urea), weekly creatinine clearance), and fatigue were assessed.
Main Results:
- Fatigue scores correlated with serum intact parathyroid hormone (iPTH) and total cholesterol levels.
- A significant correlation was observed between weekly creatinine clearance (C(cr)) and fatigue symptoms.
- Weekly C(cr) demonstrated a stronger association with fatigue than Kt/V(urea).
Conclusions:
- Dialysis adequacy is a key factor in the development of chronic fatigue among PD patients.
- Weekly creatinine clearance is a more sensitive indicator of fatigue than Kt/V(urea) in this cohort.
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