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[Study on the quality standards for xianghe suppository].

Y Deng1, L Yang, X Qiu

  • 1Guangdong Provincial Hospital of TCM, Guangzhou 510120.

Zhong Yao Cai = Zhongyaocai = Journal of Chinese Medicinal Materials
|January 22, 2002
PubMed
Summary
This summary is machine-generated.

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This study establishes quality control methods for Xianghe suppositories using Thin Layer Chromatography (TLC) and High-Performance Liquid Chromatography (HPLC). These validated techniques ensure the safety and efficacy of this traditional Chinese medicine formulation.

Area of Science:

  • Pharmacognosy
  • Analytical Chemistry
  • Traditional Chinese Medicine

Context:

  • Xianghe suppository is a traditional Chinese medicine formulation requiring stringent quality control.
  • Existing quality assessment methods may not be sufficiently robust for modern pharmaceutical standards.

Purpose:

  • To establish reliable analytical methods for the quality control of Xianghe suppository.
  • To identify key marker compounds and develop quantitative assays for ensuring product consistency.

Summary:

  • Thin Layer Chromatography (TLC) methods were developed for the identification of Rhizoma Coptidis, Radix Sophorae Flavescentis, and Flos Caryophylli.
  • A High-Performance Liquid Chromatography (HPLC) method was established for the accurate determination of berberine and palmatine.

Related Experiment Videos

  • The developed methods utilize a specific mobile phase (acetonitrile-water) and UV detection at 345 nm, proving suitable for quality control.
  • Impact:

    • Provides validated analytical methods for Xianghe suppository quality assurance.
    • Contributes to the standardization and safety of traditional Chinese medicine products.
    • Facilitates consistent production and therapeutic efficacy of Xianghe suppositories.