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Updated: Sep 2, 2026

Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts
Published on: October 21, 2022
[Postmortem evaluation of corneal astigmatism after astigmatism oriented penetrating keratoplasty]
J A Reichelt1, G Grütters, B Nölle
1Klinik für Ophthalmologie an der Christian-Albrechts-Universität Kiel, Hegewischstrasse 2, 24105 Kiel. jreichelt@ophthalmol.uni-kiel.de
Background:
Reduction of astigmatism following penetrating keratoplasty can be achieved if the graft is oriented according to astigmatism parameters in donor and host (AOPKP). Postmortem evaluation of these parameters is therefore essential. The aim of our investigation was to compare postmortem measurements using a hand-held keratometer with those of the living donor's astigmatism.
Method:
The 72-year-old female patient had undergone AOPKP on her right eye. After death the astigmatism in the right eye was evaluated 4.5 h postmortem using a hand-held keratometer. After explantation, the eyeball was examined by computer-assisted topography (TMS-1).
Results/Conclusion:
We could show that hand keratometry in situ is reliable for evaluating astigmatism in donor eyes after death. As far as our AOPKP study is concerned, these results are of great interest. Reduction of postoperative astigmatism following penetrating keratoplasty is only possible if data on astigmatism of the donor and host corneas are available.

