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Updated: Aug 1, 2026

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Screening of Axonal Degeneration in Carpal Tunnel Syndrome Using Ultrasonography and Nerve Conduction Studies
Published on: January 11, 2019
Postoperative nerve conduction changes after open and endoscopic carpal tunnel release.
S Uchiyama1, H Toriumi, H Nakagawa
1Suwa Red Cross Hospital, Suwa-City, Nagano-Prefecture, Japan. sigeharu-utiyama@suwa.jrc.or.jp
Summary
Surgical treatment for carpal tunnel syndrome using endoscopic carpal tunnel release (ECTR) or open carpal tunnel release (OCTR) shows similar nerve conduction improvements. However, ECTR carries a risk of nerve damage, with one case showing delayed motor distal latency.
Area of Science:
- Neurology
- Neurosurgery
- Orthopedics
Background:
- Idiopathic carpal tunnel syndrome (CTS) is a common condition affecting the median nerve.
- Surgical intervention is a primary treatment for CTS, with open carpal tunnel release (OCTR) and endoscopic carpal tunnel release (ECTR) being common methods.
Purpose of the Study:
- To compare the efficacy of OCTR versus ECTR in improving nerve conduction parameters in CTS patients.
- To assess changes in motor distal latency (MDL), sensory nerve conduction velocity (SCV), compound muscle action potential (CMAP), and sensory nerve action potential (SNAP) amplitudes post-surgery.
Main Methods:
- A study involving sixty-six hands of sixty-six patients diagnosed with idiopathic CTS.
- Patients were divided into ECTR and OCTR groups, with pre-operative and 1, 3, 6, and 12-month post-operative evaluations.
- Nerve conduction studies were performed to measure key electrophysiological parameters.
Main Results:
- No statistically significant differences in MDL, SCV, CMAP, or SNAP recovery were observed between ECTR and OCTR groups at any follow-up point.
- One patient in the ECTR group, who required conversion to OCTR, experienced delayed MDL and reduced CMAP amplitude.
- Electrophysiological improvements were noted in both surgical groups over the 12-month period.
Conclusions:
- Both ECTR and OCTR demonstrate comparable long-term improvements in nerve conduction for CTS patients.
- ECTR is associated with a potential risk of nerve damage, as evidenced by a case report.
- While overall recovery is similar, a slightly faster improvement trend may favor OCTR, though further investigation is warranted.

