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Frontal sinus obliteration with hydroxyapatite cement.

Guy J Petruzzelli1, James A Stankiewicz

  • 1Department of Otolaryngology-Head and Neck Surgery, Loyola University Medical Center, 2160 South First Avenue, Maywood, IL 60153, U.S.A. gpetruz@lumc.edu

The Laryngoscope
|January 22, 2002
PubMed
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Hydroxyapatite cement effectively obliterates the frontal sinus, offering a safe alternative to autologous fat grafts. This study shows high patient satisfaction and no implant removal due to infection.

Area of Science:

  • Otolaryngology
  • Neurosurgery
  • Biomaterials Science

Background:

  • Autologous fat grafts have been used for frontal sinus obliteration.
  • Complications can arise from fat graft resorption and infection.
  • Alternative materials are needed for effective and safe frontal sinus obliteration.

Purpose of the Study:

  • To evaluate hydroxyapatite cement as an alternative to autologous fat for frontal sinus obliteration.
  • To assess the efficacy and safety of hydroxyapatite cement in patients with trauma or chronic suppuration.
  • To compare outcomes with traditional methods.

Main Methods:

  • Prospective analysis of 11 patients undergoing frontal sinus obliteration with hydroxyapatite cement.
  • Inclusion of a vascularized pericardial flap for sinus floor reconstruction.

Related Experiment Videos

  • Follow-up included physical examinations, monitoring for infections, and 12-month radiographs.
  • Main Results:

    • 91% of patients reported complete symptom resolution.
    • No clinical or radiographic evidence of recurrent frontal sinusitis was observed.
    • No implants required removal during a mean follow-up of 27 months.

    Conclusions:

    • Hydroxyapatite cement is effective for full-thickness frontal sinus defect reconstruction.
    • The pericranial flap may prevent implant infection.
    • Hydroxyapatite cement offers advantages of no donor site morbidity and potential osseointegration.