Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drugs Used in Upper Respiratory Disorders: Overview01:16

Drugs Used in Upper Respiratory Disorders: Overview

988
Upper respiratory tract disorders, including viral infections and allergic rhinitis, cause significant discomfort and disrupt daily life. Managing these conditions involves a variety of drugs, such as antihistamines, intranasal steroids, decongestants, antitussives, expectorants, and mucolytics. Specific examples of drugs in each category are provided.
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
988
Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

159
Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin,...
159
Drugs Used in Lower Respiratory Disorders: Overview01:17

Drugs Used in Lower Respiratory Disorders: Overview

1.5K
Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
1.5K
Asthma-I: Introduction01:29

Asthma-I: Introduction

3.7K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
3.7K
Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids01:25

Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids

2.0K
Inhaled corticosteroids (ICS) are anti-inflammatory drugs used primarily in treating persistent asthma and providing long-term maintenance. They target the bronchial mucosa, the lining of the airways, to control inflammation, a critical factor in asthma progression and exacerbation.
ICS work through a multifaceted mechanism of action. They suppress the inflammatory response caused by the proliferation of TH cells. They also reduce the transcription of the IL-2 gene, which is involved in the...
2.0K
Chronic Pharyngitis01:23

Chronic Pharyngitis

14.7K
Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
14.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same authorSame journal

Systemic Corticosteroids in the Management of Sinonasal Disease: An Evidence-Based Expert Review.

International forum of allergy & rhinology·2026
Same author

Spontaneous gastric balloon hyperinflation causing renal infarct.

iGIE : innovation, investigation and insights·2026
Same author

The importance of axial rotation of the lower limb : a systematic review of measurement methods.

The bone & joint journal·2026
Same author

Reciprocal adaptation is critical in enhancing S. aureus and P. aeruginosa biofilm biomass.

Archives of microbiology·2026
Same author

Exploration of Real-World Data Sources in Latin America, Middle East and North Africa, and Asia Pacific, to Support Oncology Evidence Generation: A Targeted Literature Review and Regional Recommendations.

Advances in therapy·2026
Same author

Gallium Protoporphyrin and Lipid Crystalline Nanoparticles Promote the Activity of Ampicillin against MRSA.

ACS infectious diseases·2026

Related Experiment Video

Updated: Mar 25, 2026

Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence
06:08

Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence

Published on: September 22, 2023

2.8K

International Consensus Statement on Allergy and Rhinology: Rhinosinusitis.

Richard R Orlandi1, Todd T Kingdom2, Peter H Hwang3

  • 1University of Utah.

International Forum of Allergy & Rhinology
|February 19, 2016
PubMed
Summary
This summary is machine-generated.

This consensus statement synthesizes current rhinosinusitis research, offering evidence-based treatment recommendations. It highlights knowledge gaps in rhinosinusitis pathophysiology and management, guiding future research efforts.

Keywords:
acute rhinosinusitischronic rhinosinusitisendoscopic sinus surgeryevidence-based medicinerecurrent acute rhinosinusitisrhinosinusitissystematic review

More Related Videos

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
03:40

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

Published on: December 20, 2024

1.7K
Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

3.1K

Related Experiment Videos

Last Updated: Mar 25, 2026

Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence
06:08

Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence

Published on: September 22, 2023

2.8K
Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
03:40

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

Published on: December 20, 2024

1.7K
Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

3.1K

Area of Science:

  • Otolaryngology
  • Allergy and Immunology
  • Rhinology

Background:

  • Growing body of rhinosinusitis (RS) research presents quality variability.
  • International experts convened to create the International Consensus Statement on Allergy and Rhinology: Rhinosinusitis (ICAR:RS).

Purpose of the Study:

  • To consolidate and critically appraise the expanding knowledge on rhinosinusitis.
  • To provide evidence-based recommendations for the medical and surgical management of RS.

Main Methods:

  • Developed evidence-based reviews with recommendations (EBRRs) for numerous RS topics.
  • Conducted evidence-based reviews (EBRs) where evidence was insufficient for EBRRs.
  • Synthesized sections and obtained author consensus on the entire manuscript.

Main Results:

  • The ICAR:RS document covers acute RS (ARS), chronic RS (CRS) with/without nasal polyps (CRSwNP/CRSsNP), recurrent acute RS (RARS), and acute exacerbation of CRS (AECRS).
  • Addresses pediatric RS, providing a comprehensive overview of the condition in children.

Conclusions:

  • ICAR:RS offers a critical review of RS literature, detailing pathophysiology and treatment recommendations.
  • Identifies significant gaps in understanding RS pathophysiology and optimal management, indicating areas for future research.
  • Notes that recommendations are often based on lower-level evidence, emphasizing the need for further investigation.