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[Pulmonary hyalinizing granuloma: a case report and a review of the literature]
1Department of Respiratory, Anzhen Hospital, Capital University of Medical Science, Beijing 100029, China.
Objective:
To highlight the characteristics of pulmonary hyalinizing granuloma (PHG).
Method:
One patient with PHG confirmed by pathological assessment was presented and relevant literatures were reviewed.
Results:
PHG is a rare disease characterized by multiple bilateral pulmonary nodules. Symptoms include cough, dyspnea, chest pain, hemoptysis, fever and fatigue. Histologically, the nodules consist of haphazard or whorled arrays of lamellar, keloid - like collagen. Evidence suggests that the nodules are the result of a chronic exaggerated immune response.
Conclusions:
PHG should be considered in patients showing multiple bilateral pulmonary nodules. The clinical course of PHG in most patients is benign. At present, there is no effective therapy.
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